Six Locked Doors explores the events leading up to the deadliest nightclub fire in American history on November 28, 1942, at the Cocoanut Grove nightclub in Boston, Massachusetts. With double the allowed occupants, locked doors, flammable materials, and other deadly conditions, the fire left 492 people dead. Through interviews with survivors who had never before spoken on camera and an extensive archive collection of photos, and unreleased footage, the film explores how corruption, greed, and a former gangster-run speakeasy led to an unimaginable tragedy.